Introducing HybridSPETM-Precipitation Technology for Pharmaceutical Bioanalytical Sample Preparation
نویسنده
چکیده
In pharmaceutical bioanalysis, researchers develop and run various assays to quantitate drugs, pharmaceutical candidates, and their metabolites in biological fluids such as serum and plasma. The data resulting from these assays are used to help determine the pharmacodynamic and pharmacokinetic properties as well as the toxic and therapeutic concentrations of existing and emerging pharmaceutical compounds in living cells, tissues, and animals. Although advances in Liquid Chromatography-Mass Spectrometry (LC-MS) technology have reaped overwhelming benefits in terms of increased throughput and sensitivity, good sample preparation continues to be a critical component of bioanalysis.
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